Epithalon
Epitalon · AEDG · Ala-Glu-Asp-Gly
Epithalon (Epitalon, Ala-Glu-Asp-Gly) is a synthetic tetrapeptide derived from a pineal gland extract (epithalamin). It is studied in vitro and in preclinical models for telomerase activity, cellular ageing and neuroendocrine function. Reagent intended exclusively for laboratory research — not intended for human consumption.
Key facts
- Class
- Tetrapeptide (4 aa)
- Origin
- Pineal extract (epithalamin)
- Form
- Lyophilised (powder)
- Status
- Research Use Only
Documented research areas
Study library
All results on PubMedEpitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity.
Al-Dulaimi S, et al. · Biogerontology · 2025
Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties.
Araj SK, et al. · International journal of molecular sciences · 2025
Epitalon-activated telomerase enhance bovine oocyte maturation rate and post-thawed embryo development.
Ullah S, et al. · Life sciences · 2025
Correction: Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity.
Al-Dulaimi S, et al. · Biogerontology · 2025
Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.
Khavinson VKh, et al. · Bulletin of experimental biology and medicine · 2003
Effect of regulatory peptides on gene transcription.
Khavinson VKh, et al. · Bulletin of experimental biology and medicine · 2003
Peptide promotes overcoming of the division limit in human somatic cell.
Khavinson VKh, et al. · Bulletin of experimental biology and medicine · 2004
DNA double-helix binds regulatory peptides similarly to transcription factors.
Khavinson V, et al. · Neuro endocrinology letters · 2005
Results retrieved live from PubMed (NCBI). Research literature only — no medical advice.
Research peptides — Research Use Only
- Not for human consumption
- Not for the diagnosis, treatment or prevention of any disease