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5 Oct 2026 · Janoshik
MOTS-c
16-amino-acid mitochondrial peptide studied in metabolic research.
MOTS-c
10 mg · 43,90 €
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Description
MOTS-c (Mitochondrial ORF of the 12S rRNA type-c) is a 16-amino-acid peptide of mitochondrial origin, studied as a research tool for metabolic homeostasis and the AMPK pathway in laboratory models. Supplied lyophilised with an independent certificate of analysis. Intended exclusively for scientific research in the laboratory — not intended for human consumption.
Research peptides — Research Use Only
- Not for human consumption
- Not for the diagnosis, treatment or prevention of any disease
Related products
Reconstitution calculator
Pre-filled for this peptide. Adjust the water added and target dose to get the volume to draw.
Calculation result
Draw the syringe to
10
units
Volume
0.1
mL
Concentration
5
mg/mL
Draws / vial
20
Level on a graduated syringe 1 mL (100 U)
This vial lasts 10 weeks
Syringe size
Target dose
the amount of peptide targeted
0.5 mg
0.5 mg = 500 mcg (µg)
Vial dosage
total peptide mass, in mg
10 mg
Bacteriostatic water
reconstitution volume, in mL
2 mL

MOTS-c — Research protocol
Mitochondrial-derived peptide
- Dose (study protocol)
- 5–10 mg per administration
- Frequency
- 3–5×/week (s.c.)
- Duration (published studies)
- 4–12 weeks (murine models)
Source : Lee et al., Cell Metabolism 2015
No published human study. Murine doses: 2.5 mg/kg twice daily i.p. (Lee 2015).
This data comes from published studies compiled for informational purposes for laboratory professionals. No dose is recommended. Not intended for human consumption or animal use.
Read the full analysis MOTS-cGet your complete protocol
Personalised numeric summary + a printable step-by-step reconstitution procedure. We email it to you as a PDF.
How It Works
1. Concentration
Divide vial amount (mcg) by water volume (mL) to get concentration (mcg/mL).
2. Volume needed
Divide desired dose by concentration to get injection volume in mL.
3. Syringe units
Multiply mL × 100 to get U-100 syringe units (IU).
Example
- 5 mg vial + 2 mL water = 2.5 mg/mL
- Want 250 mcg (0.25 mg)?
- 0.25 ÷ 2.5 = 0.1 mL
- 0.1 mL = 10 units on a U-100 syringe
Research Use Only
This calculator is for research purposes only. Not medical advice.
Common Conversions
- 1 mg
- 1,000 mcg
- 500 mcg
- 0.5 mg
- 250 mcg
- 0.25 mg
- 100 mcg
- 0.1 mg
Syringe Units
- 0.3 mL syringe
- 30 units
- 0.5 mL syringe
- 50 units
- 1.0 mL syringe
- 100 units
Volumetric conversion tool for laboratory handling. Not any human or animal administration advice. Research use only.
Why this research peptide
Mitochondrial peptide
Encoded by the mitochondrial genome, MOTS-c belongs to the family of mitochondrial-derived peptides (MDP).
AMPK pathway studied
Documented in vitro for activation of AMP-activated protein kinase and regulation of energy metabolism.
Metabolic homeostasis
Studied in laboratory models for its role in glucose metabolism regulation.
Verified purity
HPLC + mass spectrometry analysis by an independent laboratory, certificate included with each batch.
Long-term storage
Lyophilised form stable up to 24 months at -20°C for prolonged laboratory storage.
Discreet logistics
Shipped from the EU, delivery within 1–2 days, tracking included and neutral packaging.
What is MOTS-c?
MOTS-c is a 16-amino-acid peptide encoded by the mitochondrial genome, belonging to the family of mitochondrial-derived peptides. It is used as a reagent to study metabolic homeostasis in laboratory models. Supplied lyophilised with an independent certificate of analysis, intended exclusively for scientific research — not intended for human consumption.
Storage & handling
Product intended exclusively for scientific research in the laboratory. Keep in its original packaging until use.
Published research data
The works below document the pharmacology of MOTS-c. They are cited as scientific context and do not constitute a product claim.
- 1
Cell Metabolism (2015) — PMID 25738459
Foundational work describing MOTS-c as a regulator of metabolic homeostasis via the AMPK pathway in preclinical models.
Mechanisms studied in research
The literature describes several pathways studied in vitro and in preclinical models. The items below summarise these mechanisms for information only, with no intended human use.
AMPK pathway
Studied for activation of AMP-activated protein kinase, a central regulator of energy metabolism.
Glucose metabolism
Documented in preclinical models for its influence on glucose homeostasis and insulin sensitivity.
Nuclear translocation
Described as migrating to the nucleus under metabolic stress, in association with antioxidant response elements.
Questions about this product
Who is this product intended for?
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How are batches verified?
What are the delivery times?
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Is the certificate of analysis provided?
PEPTIDESunderstanding before use
The clear, source-backed guide to understanding how they work, their uses, their benefits, their risks and the essential precautions — before you get started.
- How peptides really work
- Their uses and what the research says
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- Risks, limits and essential precautions





